Beyond market averages, investors seeking exceptional growth focus on the art of stock selection. The right picks can significantly contribute to the expansion of your wealth.
In the latest session, Upstream Bio Inc (NASDAQ: UPB) closed at $27.15 down -0.62% from its previous closing price of $27.32. In other words, the price has decreased by -$0.62 from its previous closing price. On the day, 0.52 million shares were traded. UPB stock price reached its highest trading level at $27.58 during the session, while it also had its lowest trading level at $26.9.
Ratios:
For a deeper understanding of Upstream Bio Inc’s stock, let’s take a closer look at its various ratios. For the most recent quarter (mrq), Quick Ratio is recorded 32.67 and its Current Ratio is at 32.67. In the meantime, Its Debt-to-Equity ratio is 0.00 whereas as Long-Term Debt/Eq ratio is at 0.00.
Upgrades & Downgrades
In the most recent recommendation for this company, Mizuho on December 18, 2025, initiated with a Outperform rating and assigned the stock a target price of $51.
On November 18, 2025, Evercore ISI started tracking the stock assigning a Outperform rating and target price of $40.
On October 14, 2025, Truist started tracking the stock assigning a Buy rating and target price of $47.Truist initiated its Buy rating on October 14, 2025, with a $47 target price.
Valuation Measures:
Investors should consider key stock statistics when deciding whether to invest or divest. In the wake of the recent closing price, UPB now has a Market Capitalization of 1467147776 and an Enterprise Value of 1096139776. For the stock, the TTM Price-to-Sale (P/S) ratio is 523.98 while its Price-to-Book (P/B) ratio in mrq is 3.87. Its current Enterprise Value per Revenue stands at 391.618 whereas that against EBITDA is -7.811.
Stock Price History:
The Beta on a monthly basis for UPB is 1.90, which has changed by 0.47956407 over the last 52 weeks, in comparison to a change of 0.15196204 over the same period for the S&P500. Over the past 52 weeks, UPB has reached a high of $30.89, while it has fallen to a 52-week low of $5.14. The 50-Day Moving Average of the stock is 3.37%, while the 200-Day Moving Average is calculated to be 67.84%.
Shares Statistics:
For the past three months, UPB has traded an average of 462.13K shares per day and 582930 over the past ten days. A total of 54.00M shares are outstanding, with a floating share count of 25.64M. Insiders hold about 52.55% of the company’s shares, while institutions hold 56.92% stake in the company. Shares short for UPB as of 1765756800 were 2983568 with a Short Ratio of 6.46, compared to 1763078400 on 2994056. Therefore, it implies a Short% of Shares Outstanding of 2983568 and a Short% of Float of 9.950000000000001.






