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The closing price of Karyopharm Therapeutics Inc (NASDAQ: KPTI) was $5.55 for the day, up 1.83% from the previous closing price of $5.45. In other words, the price has increased by $1.83 from its previous closing price. On the day, 0.11 million shares were traded. KPTI stock price reached its highest trading level at $5.66 during the session, while it also had its lowest trading level at $5.3711.
Ratios:
Our analysis of KPTI’s different ratios will help us gain a deeper understanding of the company. For the most recent quarter (mrq), Quick Ratio is recorded 0.98 and its Current Ratio is at 1.03.
Insider Transactions:
Also, insider trades can serve as a great indicator of what management thinks about the future direction of a stock’s price. A recent insider transaction in this stock occurred on Oct 01 ’25 when Abate Kristin sold 362 shares for $6.30 per share. The transaction valued at 2,279 led to the insider holds 10,046 shares of the business.
Paulson Richard A. sold 1,257 shares of KPTI for $8,083 on Sep 15 ’25. The President and CEO now owns 84,046 shares after completing the transaction at $6.43 per share. On Sep 15 ’25, another insider, Mano Michael, who serves as the SVP, General Counsel&Secretary of the company, sold 234 shares for $6.43 each. As a result, the insider received 1,505 and left with 21,425 shares of the company.
Valuation Measures:
Investors should consider key stock statistics when deciding whether to invest or divest. In the wake of the recent closing price, KPTI now has a Market Capitalization of 94632368 and an Enterprise Value of 318677376. For the stock, the TTM Price-to-Sale (P/S) ratio is 0.66. Its current Enterprise Value per Revenue stands at 2.236 whereas that against EBITDA is -3.071.
Stock Price History:
The Beta on a monthly basis for KPTI is 0.24, which has changed by -0.5700197 over the last 52 weeks, in comparison to a change of 0.12159383 over the same period for the S&P500. Over the past 52 weeks, KPTI has reached a high of $13.20, while it has fallen to a 52-week low of $3.51. The 50-Day Moving Average of the stock is -6.97%, while the 200-Day Moving Average is calculated to be -1.38%.
Shares Statistics:
KPTI traded an average of 169.98K shares per day over the past three months and 108930 shares per day over the past ten days. A total of 17.05M shares are outstanding, with a floating share count of 14.69M. Insiders hold about 13.87% of the company’s shares, while institutions hold 40.55% stake in the company. Shares short for KPTI as of 1763078400 were 716400 with a Short Ratio of 4.21, compared to 1760486400 on 1438931. Therefore, it implies a Short% of Shares Outstanding of 716400 and a Short% of Float of 4.22.
Earnings Estimates
. The current rating of Karyopharm Therapeutics Inc (KPTI) is the result of assessments by 2.0 analysts actively engaged in evaluating its market dynamics.The consensus estimate for the next quarter is -$1.56, with high estimates of -$1.56 and low estimates of -$1.56.
Analysts are recommending an EPS of between -$11.46 and -$12.61 for the fiscal current year, implying an average EPS of -$12.03. EPS for the following year is -$4.86, with 2.0 analysts recommending between -$4.48 and -$5.25.
Revenue Estimates
It is expected that $90B in revenue will be generated in. The current quarter, according to 6 analysts. It ranges from a high estimate of $39.36M to a low estimate of $33.35M. As of. The current estimate, Karyopharm Therapeutics Inc’s year-ago sales were $30.54MFor the next quarter, 6 analysts are estimating revenue of $35.5M. There is a high estimate of $38.5M for the next quarter, whereas the lowest estimate is $32.5M.
A total of 6 analysts have provided revenue estimates for KPTI’s current fiscal year. The highest revenue estimate was $151.34M, while the lowest revenue estimate was $145.34M, resulting in an average revenue estimate of $147.83M. In the same quarter a year ago, actual revenue was $145.24MBased on 6 analysts’ estimates, the company’s revenue will be $152.54M in the next fiscal year. The high estimate is $172M and the low estimate is $132.26M.






