Market Watch Highlights: Septerna Inc (SEPN) Ends on an% Downturn Note at 12.1

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As of close of business last night, Septerna Inc’s stock clocked out at $12.1, down -1.47% from its previous closing price of $12.28. In other words, the price has decreased by -$1.47 from its previous closing price. On the day, 0.2 million shares were traded. SEPN stock price reached its highest trading level at $12.295 during the session, while it also had its lowest trading level at $11.7.

Ratios:

To gain a deeper understanding of SEPN’s stock, we examine its different ratios. For the most recent quarter (mrq), Quick Ratio is recorded 22.09 and its Current Ratio is at 22.09. In the meantime, Its Debt-to-Equity ratio is 0.07 whereas as Long-Term Debt/Eq ratio is at 0.06.

Upgrades & Downgrades

In addition, analysts’ ratings and any changes thereto give investors an idea of the stock’s future direction. In the most recent recommendation for this company, H.C. Wainwright on June 23, 2025, initiated with a Buy rating and assigned the stock a target price of $26.

On February 18, 2025, Wells Fargo Downgraded its rating to Equal Weight which previously was Overweight but kept the price unchanged to $14.

On November 19, 2024, Wells Fargo started tracking the stock assigning a Overweight rating and target price of $43.Wells Fargo initiated its Overweight rating on November 19, 2024, with a $43 target price.

Insider Transactions:

Investing in insider trades can also provide an investor with insight into how management views future stock prices. A recent insider transaction in this stock occurred on Mar 07 ’25 when Ezekowitz Alan bought 13,319 shares for $6.93 per share. The transaction valued at 92,270 led to the insider holds 117,420 shares of the business.

Ezekowitz Alan bought 41,355 shares of SEPN for $248,130 on Mar 06 ’25. The Director now owns 104,101 shares after completing the transaction at $6.00 per share. On Mar 05 ’25, another insider, Ezekowitz Alan, who serves as the Director of the company, bought 37,835 shares for $5.82 each. As a result, the insider paid 220,260 and bolstered with 62,746 shares of the company.

Valuation Measures:

Investors should consider key stock statistics when deciding whether to invest or divest. In the wake of the recent closing price, SEPN now has a Market Capitalization of 539479744 and an Enterprise Value of 237490128. For the stock, the TTM Price-to-Sale (P/S) ratio is 739.01 while its Price-to-Book (P/B) ratio in mrq is 1.43. Its current Enterprise Value per Revenue stands at 327.121 whereas that against EBITDA is -2.361.

Stock Price History:

Over the past 52 weeks, SEPN has reached a high of $28.99, while it has fallen to a 52-week low of $4.17. The 50-Day Moving Average of the stock is 2.39%, while the 200-Day Moving Average is calculated to be -5.04%.

Shares Statistics:

It appears that SEPN traded 352.01K shares on average per day over the past three months and 214320 shares per day over the past ten days. A total of 44.57M shares are outstanding, with a floating share count of 26.76M. Insiders hold about 39.99% of the company’s shares, while institutions hold 63.18% stake in the company. Shares short for SEPN as of 1755216000 were 3162368 with a Short Ratio of 8.98, compared to 1752537600 on 3740655. Therefore, it implies a Short% of Shares Outstanding of 3162368 and a Short% of Float of 12.25.

Earnings Estimates

The dynamic stock of Septerna Inc (SEPN) is currently being evaluated by a team of 5.0 analysts, each contributing to its current rating.The consensus estimate for the next quarter is -$0.17, with high estimates of $0.87 and low estimates of -$0.52.

Analysts are recommending an EPS of between $2.23 and -$1.9 for the fiscal current year, implying an average EPS of -$0.35. EPS for the following year is -$2.07, with 5.0 analysts recommending between -$1.52 and -$3.05.

Revenue Estimates

In the current quarter, 4 analysts expect revenue to total $75M. It ranges from a high estimate of $195M to a low estimate of $5M. As of the current estimate, Septerna Inc’s year-ago sales were $176k

A total of 5 analysts have provided revenue estimates for SEPN’s current fiscal year. The highest revenue estimate was $195M, while the lowest revenue estimate was $10M, resulting in an average revenue estimate of $85.89M. In the same quarter a year ago, actual revenue was $1.07M

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