Financial Metrics Exploration: Understanding Alnylam Pharmaceuticals Inc (ALNY) Through Ratios

Kevin Freeman

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The closing price of Alnylam Pharmaceuticals Inc (NASDAQ: ALNY) was $415.21 for the day, down -3.44% from the previous closing price of $430.02. In other words, the price has decreased by -$3.44 from its previous closing price. On the day, 1.61 million shares were traded. ALNY stock price reached its highest trading level at $433.305 during the session, while it also had its lowest trading level at $414.45.

Ratios:

Our analysis of ALNY’s different ratios will help us gain a deeper understanding of the company. It provided that stocks Price–to–Cash (P/C) ratio for the trailing twelve months (TTM) is standing at 20.13 whereas its Price-to-Free Cash Flow (P/FCF) for the term is 247.81. For the most recent quarter (mrq), Quick Ratio is recorded 2.49 and its Current Ratio is at 2.54. In the meantime, Its Debt-to-Equity ratio is 11.86 whereas as Long-Term Debt/Eq ratio is at 11.17.

On August 04, 2025, Oppenheimer Upgraded its rating to Outperform which previously was Perform but kept the price unchanged to $490.

Insider Transactions:

Also, insider trades can serve as a great indicator of what management thinks about the future direction of a stock’s price. A recent insider transaction in this stock occurred on Nov 17 ’25 when Fitzgerald Kevin Joseph sold 12,128 shares for $452.18 per share. The transaction valued at 5,483,990 led to the insider holds 21,264 shares of the business.

Fitzgerald Kevin Joseph bought 12,128 shares of ALNY for $5,445,472 on Nov 17 ’25. On Nov 12 ’25, another insider, Greenstreet Yvonne, who serves as the Chief Executive Officer of the company, sold 15,650 shares for $453.69 each. As a result, the insider received 7,100,322 and left with 65,409 shares of the company.

Valuation Measures:

Investors should consider key stock statistics when deciding whether to invest or divest. In the wake of the recent closing price, ALNY now has a Market Capitalization of 54854975488 and an Enterprise Value of 56860270592. As of this moment, Alnylam’s Price-to-Earnings (P/E) ratio for their current fiscal year is 1727.16, and their Forward P/E ratio for the next fiscal year is 55.16. For the stock, the TTM Price-to-Sale (P/S) ratio is 17.09 while its Price-to-Book (P/B) ratio in mrq is 233.96. Its current Enterprise Value per Revenue stands at 17.713 whereas that against EBITDA is 177.123.

Stock Price History:

The Beta on a monthly basis for ALNY is 0.31, which has changed by 0.6919929 over the last 52 weeks, in comparison to a change of 0.12529528 over the same period for the S&P500. Over the past 52 weeks, ALNY has reached a high of $495.55, while it has fallen to a 52-week low of $205.87. The 50-Day Moving Average of the stock is -8.92%, while the 200-Day Moving Average is calculated to be 15.51%.

Shares Statistics:

ALNY traded an average of 1.12M shares per day over the past three months and 1162220 shares per day over the past ten days. A total of 131.79M shares are outstanding, with a floating share count of 129.77M. Insiders hold about 1.77% of the company’s shares, while institutions hold 99.36% stake in the company. Shares short for ALNY as of 1763078400 were 4279250 with a Short Ratio of 3.83, compared to 1760486400 on 3993922. Therefore, it implies a Short% of Shares Outstanding of 4279250 and a Short% of Float of 4.2600001999999995.

Earnings Estimates

. The current assessment of Alnylam Pharmaceuticals Inc (ALNY) involves the perspectives of 11.0 analysts closely monitoring its market dynamics.The consensus estimate for the next quarter is $2.09, with high estimates of $2.55 and low estimates of $1.55.

Analysts are recommending an EPS of between $5.99 and $3.76 for the fiscal current year, implying an average EPS of $4.96. EPS for the following year is $10.61, with 12.0 analysts recommending between $13.86 and $6.44.

Revenue Estimates

It is expected that $90B in revenue will be generated in. The current quarter, according to 20 analysts. It ranges from a high estimate of $1.61B to a low estimate of $1.04B. As of. The current estimate, Alnylam Pharmaceuticals Inc’s year-ago sales were $593.17MFor the next quarter, 20 analysts are estimating revenue of $1.22B. There is a high estimate of $1.31B for the next quarter, whereas the lowest estimate is $1.11B.

A total of 25 analysts have provided revenue estimates for ALNY’s current fiscal year. The highest revenue estimate was $4.23B, while the lowest revenue estimate was $3.42B, resulting in an average revenue estimate of $3.74B. In the same quarter a year ago, actual revenue was $2.25BBased on 24 analysts’ estimates, the company’s revenue will be $5.35B in the next fiscal year. The high estimate is $6.12B and the low estimate is $4.34B.

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