The pursuit of outperformance leads many investors to carefully choose individual stocks. Picking the right ones can be a game-changer for growing your wealth.
Agios Pharmaceuticals Inc (NASDAQ: AGIO) closed the day trading at $25.45 down -2.45% from the previous closing price of $26.09. In other words, the price has decreased by -$2.45 from its previous closing price. On the day, 1.37 million shares were traded. AGIO stock price reached its highest trading level at $26.36 during the session, while it also had its lowest trading level at $25.405.
Ratios:
For a better understanding of AGIO, let’s look at its different ratios. For the most recent quarter (mrq), Quick Ratio is recorded 13.39 and its Current Ratio is at 13.82. In the meantime, Its Debt-to-Equity ratio is 0.03 whereas as Long-Term Debt/Eq ratio is at 0.02.
On November 20, 2025, Leerink Partners Upgraded its rating to Outperform which previously was Market Perform but kept the price unchanged to $34.
RBC Capital Mkts Downgraded its Outperform to Sector Perform on November 19, 2025, while the target price for the stock was maintained at $28.
Insider Transactions:
The insider trade also gives investors a glimpse into the future direction of stock prices, which can be beneficial to investors. A recent insider transaction in this stock occurred on Nov 12 ’25 when Scadden David sold 200 shares for $43.84 per share. The transaction valued at 8,768 led to the insider holds 17,603 shares of the business.
Gheuens Sarah sold 2,454 shares of AGIO for $107,436 on Nov 11 ’25. The Chief Medical Officer now owns 61,727 shares after completing the transaction at $43.78 per share. On Nov 11 ’25, another insider, SARAH GHEUENS, who serves as the Officer of the company, bought 2,454 shares for $43.78 each.
Valuation Measures:
Investors should consider key stock statistics when deciding whether to invest or divest. In the wake of the recent closing price, AGIO now has a Market Capitalization of 1484086528 and an Enterprise Value of 575741504. For the stock, the TTM Price-to-Sale (P/S) ratio is 33.13 while its Price-to-Book (P/B) ratio in mrq is 1.15. Its current Enterprise Value per Revenue stands at 12.854 whereas that against EBITDA is -1.224.
Stock Price History:
The Beta on a monthly basis for AGIO is 0.90, which has changed by -0.27143258 over the last 52 weeks, in comparison to a change of 0.15905356 over the same period for the S&P500. Over the past 52 weeks, AGIO has reached a high of $46.00, while it has fallen to a 52-week low of $22.24. The 50-Day Moving Average of the stock is -29.52%, while the 200-Day Moving Average is calculated to be -26.18%.
Shares Statistics:
Over the past 3-months, AGIO traded about 1.25M shares per day on average, while over the past 10 days, AGIO traded about 1193770 shares per day. A total of 58.28M shares are outstanding, with a floating share count of 54.95M. Insiders hold about 5.77% of the company’s shares, while institutions hold 101.98% stake in the company. Shares short for AGIO as of 1764288000 were 5466677 with a Short Ratio of 4.38, compared to 1761868800 on 4601630. Therefore, it implies a Short% of Shares Outstanding of 5466677 and a Short% of Float of 9.4399996.
Earnings Estimates
A detailed examination of Agios Pharmaceuticals Inc (AGIO) is currently in progress, with 8.0 analysts providing valuable insights into its market dynamics.The consensus estimate for the next quarter is -$1.88, with high estimates of -$1.7 and low estimates of -$2.04.
Analysts are recommending an EPS of between -$5.58 and -$7.36 for the fiscal current year, implying an average EPS of -$7.01. EPS for the following year is -$6.57, with 10.0 analysts recommending between -$4.82 and -$8.37.
Revenue Estimates
10 analysts predict $12.04M in revenue for. The current quarter. It ranges from a high estimate of $13.4M to a low estimate of $9M. As of. The current estimate, Agios Pharmaceuticals Inc’s year-ago sales were $10.73MFor the next quarter, 10 analysts are estimating revenue of $16.04M. There is a high estimate of $18.07M for the next quarter, whereas the lowest estimate is $14.37M.
A total of 10 analysts have provided revenue estimates for AGIO’s current fiscal year. The highest revenue estimate was $47.5M, while the lowest revenue estimate was $43.34M, resulting in an average revenue estimate of $46.1M. In the same quarter a year ago, actual revenue was $36.5MBased on 10 analysts’ estimates, the company’s revenue will be $108.57M in the next fiscal year. The high estimate is $191.3M and the low estimate is $67.25M.






