Investors with the goal of beating the broader market often turn to stock selection. Strategic choices in individual stocks can have a profound impact on your wealth.
The closing price of Septerna Inc (NASDAQ: SEPN) was $24.88 for the day, down -1.66% from the previous closing price of $25.3. In other words, the price has decreased by -$1.66 from its previous closing price. On the day, 1.07 million shares were traded. SEPN stock price reached its highest trading level at $25.54 during the session, while it also had its lowest trading level at $24.66.
Ratios:
Our analysis of SEPN’s different ratios will help us gain a deeper understanding of the company. It provided that stocks Price–to–Cash (P/C) ratio for the trailing twelve months (TTM) is standing at 2.35 whereas its Price-to-Free Cash Flow (P/FCF) for the term is 10.80. For the most recent quarter (mrq), Quick Ratio is recorded 6.53 and its Current Ratio is at 6.53. In the meantime, Its Debt-to-Equity ratio is 0.06 whereas as Long-Term Debt/Eq ratio is at 0.06.
Upgrades & Downgrades
In the most recent recommendation for this company, Raymond James on December 19, 2025, initiated with a Strong Buy rating and assigned the stock a target price of $38.
On December 15, 2025, Truist started tracking the stock assigning a Buy rating and target price of $34.
Insider Transactions:
Also, insider trades can serve as a great indicator of what management thinks about the future direction of a stock’s price. A recent insider transaction in this stock occurred on Nov 10 ’25 when Long Daniel D. sold 3,501 shares for $18.06 per share. The transaction valued at 63,223 led to the insider holds 92,911 shares of the business.
DANIEL DAVID LONG bought 3,501 shares of SEPN for $63,223 on Nov 10 ’25. On Mar 07 ’25, another insider, Ezekowitz Alan, who serves as the Director of the company, bought 13,319 shares for $6.93 each. As a result, the insider paid 92,270 and bolstered with 117,420 shares of the company.
Valuation Measures:
Investors should consider key stock statistics when deciding whether to invest or divest. In the wake of the recent closing price, SEPN now has a Market Capitalization of 1113981824 and an Enterprise Value of 663745920. For the stock, the TTM Price-to-Sale (P/S) ratio is 50.52 while its Price-to-Book (P/B) ratio in mrq is 2.86. Its current Enterprise Value per Revenue stands at 30.109 whereas that against EBITDA is -7.551.
Stock Price History:
The Beta on a monthly basis for SEPN is 3.81, which has changed by 0.49174523 over the last 52 weeks, in comparison to a change of 0.19226205 over the same period for the S&P500. Over the past 52 weeks, SEPN has reached a high of $30.50, while it has fallen to a 52-week low of $4.17. The 50-Day Moving Average of the stock is -0.43%, while the 200-Day Moving Average is calculated to be 61.57%.
Shares Statistics:
SEPN traded an average of 312.19K shares per day over the past three months and 207680 shares per day over the past ten days. A total of 44.64M shares are outstanding, with a floating share count of 26.95M. Insiders hold about 39.81% of the company’s shares, while institutions hold 63.27% stake in the company. Shares short for SEPN as of 1767139200 were 1427098 with a Short Ratio of 4.57, compared to 1764288000 on 1477425. Therefore, it implies a Short% of Shares Outstanding of 1427098 and a Short% of Float of 5.4899998.
Earnings Estimates
Its stock is currently analyzed by 3.0 different market analysts. The consensus estimate for the next quarter is -$0.03, with high estimates of $0.09 and low estimates of -$0.21.
Analysts are recommending an EPS of between -$0.78 and -$1.07 for the fiscal current year, implying an average EPS of -$0.94. EPS for the following year is -$0.36, with 4.0 analysts recommending between $0.31 and -$1.27.
Revenue Estimates
A total of 8 analysts have provided revenue estimates for SEPN’s current fiscal year. The highest revenue estimate was $46.83M, while the lowest revenue estimate was $21.8M, resulting in an average revenue estimate of $38.99M. In the same quarter a year ago, actual revenue was $1.07M
