Market Insight: Agios Pharmaceuticals Inc (AGIO)’s Notable Gain%, Closing at $27.49

Kevin Freeman

Beyond market trends, investors looking for superior returns explore the world of stock picking. The right selections can be a powerful driver for wealth accumulation.

In the latest session, Agios Pharmaceuticals Inc (NASDAQ: AGIO) closed at $27.49 up 1.89% from its previous closing price of $26.98. In other words, the price has increased by $1.89 from its previous closing price. On the day, 1.2 million shares were traded. AGIO stock price reached its highest trading level at $27.72 during the session, while it also had its lowest trading level at $27.0.

Ratios:

For a deeper understanding of Agios Pharmaceuticals Inc’s stock, let’s take a closer look at its various ratios. For the most recent quarter (mrq), Quick Ratio is recorded 13.39 and its Current Ratio is at 13.82. In the meantime, Its Debt-to-Equity ratio is 0.03 whereas as Long-Term Debt/Eq ratio is at 0.02.

On November 20, 2025, Leerink Partners Upgraded its rating to Outperform which previously was Market Perform but kept the price unchanged to $34.

RBC Capital Mkts Downgraded its Outperform to Sector Perform on November 19, 2025, while the target price for the stock was maintained at $28.

Insider Transactions:

Additionally, insider trades can be beneficial to investors who want to learn what the management thinks about stock prices in the future. A recent insider transaction in this stock occurred on Nov 12 ’25 when Scadden David sold 200 shares for $43.84 per share. The transaction valued at 8,768 led to the insider holds 17,603 shares of the business.

Gheuens Sarah sold 2,454 shares of AGIO for $107,436 on Nov 11 ’25. The Chief Medical Officer now owns 61,727 shares after completing the transaction at $43.78 per share. On Nov 11 ’25, another insider, SARAH GHEUENS, who serves as the Officer of the company, bought 2,454 shares for $43.78 each.

Valuation Measures:

Investors should consider key stock statistics when deciding whether to invest or divest. In the wake of the recent closing price, AGIO now has a Market Capitalization of 1603046656 and an Enterprise Value of 694701696. For the stock, the TTM Price-to-Sale (P/S) ratio is 35.79 while its Price-to-Book (P/B) ratio in mrq is 1.25. Its current Enterprise Value per Revenue stands at 15.51 whereas that against EBITDA is -1.477.

Stock Price History:

The Beta on a monthly basis for AGIO is 0.89, which has changed by -0.5424792 over the last 52 weeks, in comparison to a change of 0.12415576 over the same period for the S&P500. Over the past 52 weeks, AGIO has reached a high of $62.45, while it has fallen to a 52-week low of $22.24. The 50-Day Moving Average of the stock is -28.77%, while the 200-Day Moving Average is calculated to be -21.11%.

Shares Statistics:

For the past three months, AGIO has traded an average of 1.22M shares per day and 4168160 over the past ten days. A total of 58.28M shares are outstanding, with a floating share count of 54.94M. Insiders hold about 5.79% of the company’s shares, while institutions hold 108.35% stake in the company. Shares short for AGIO as of 1763078400 were 4331538 with a Short Ratio of 3.56, compared to 1760486400 on 4973477. Therefore, it implies a Short% of Shares Outstanding of 4331538 and a Short% of Float of 7.48.

Earnings Estimates

. The current assessment of Agios Pharmaceuticals Inc (AGIO) involves the perspectives of 9.0 analysts closely monitoring its market dynamics.The consensus estimate for the next quarter is -$1.93, with high estimates of -$1.75 and low estimates of -$2.04.

Analysts are recommending an EPS of between -$5.58 and -$7.36 for the fiscal current year, implying an average EPS of -$7.03. EPS for the following year is -$6.66, with 9.0 analysts recommending between -$4.82 and -$8.37.

Revenue Estimates

A total of 10 analysts believe the company’s revenue will be $12.04M this quarter.It ranges from a high estimate of $13.4M to a low estimate of $9M. As of. The current estimate, Agios Pharmaceuticals Inc’s year-ago sales were $10.73MFor the next quarter, 10 analysts are estimating revenue of $16.04M. There is a high estimate of $18.07M for the next quarter, whereas the lowest estimate is $14.37M.

A total of 10 analysts have provided revenue estimates for AGIO’s current fiscal year. The highest revenue estimate was $47.5M, while the lowest revenue estimate was $43.34M, resulting in an average revenue estimate of $46.1M. In the same quarter a year ago, actual revenue was $36.5MBased on 10 analysts’ estimates, the company’s revenue will be $108.57M in the next fiscal year. The high estimate is $191.3M and the low estimate is $67.25M.

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