Investors with the goal of beating the broader market often turn to stock selection. Strategic choices in individual stocks can have a profound impact on your wealth.
After finishing at $27.14 in the prior trading day, Upstream Bio Inc (NASDAQ: UPB) closed at $27.2, up 0.22%. In other words, the price has increased by $0.22 from its previous closing price. On the day, 1.17 million shares were traded. UPB stock price reached its highest trading level at $27.945 during the session, while it also had its lowest trading level at $26.685.
Ratios:
Our goal is to gain a better understanding of UPB by taking a closer look at its different ratios. For the most recent quarter (mrq), Quick Ratio is recorded 32.67 and its Current Ratio is at 32.67. In the meantime, Its Debt-to-Equity ratio is 0.00 whereas as Long-Term Debt/Eq ratio is at 0.00.
Upgrades & Downgrades
In the most recent recommendation for this company, Evercore ISI on November 18, 2025, initiated with a Outperform rating and assigned the stock a target price of $40.
On October 14, 2025, Truist started tracking the stock assigning a Buy rating and target price of $47.
Valuation Measures:
Investors should consider key stock statistics when deciding whether to invest or divest. In the wake of the recent closing price, UPB now has a Market Capitalization of 1469849728 and an Enterprise Value of 1098301312. For the stock, the TTM Price-to-Sale (P/S) ratio is 524.95 while its Price-to-Book (P/B) ratio in mrq is 3.88. Its current Enterprise Value per Revenue stands at 392.391 whereas that against EBITDA is -7.826.
Stock Price History:
The Beta on a monthly basis for UPB is 1.94, which has changed by 0.38257766 over the last 52 weeks, in comparison to a change of 0.12838376 over the same period for the S&P500. Over the past 52 weeks, UPB has reached a high of $29.89, while it has fallen to a 52-week low of $5.14. The 50-Day Moving Average of the stock is 11.69%, while the 200-Day Moving Average is calculated to be 80.61%.
Shares Statistics:
The stock has traded on average 440.94K shares per day over the past 3-months and 478100 shares per day over the last 10 days, according to various share statistics. A total of 54.00M shares are outstanding, with a floating share count of 25.64M. Insiders hold about 52.55% of the company’s shares, while institutions hold 56.56% stake in the company. Shares short for UPB as of 1764288000 were 2773635 with a Short Ratio of 6.29, compared to 1761868800 on 2929476. Therefore, it implies a Short% of Shares Outstanding of 2773635 and a Short% of Float of 9.25.






